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   Sep 11

Time to slap on the BROCCOLI? Compound in vegetable found to protect against sunburn and skin cancer

Compound called sulforaphane prevents growth of cancer cells

Also triggers chemoprotective genes – such as the Nrf2 gene

Nrf2 protects healthy tissue from the toxic effects of chemotherapy drugs

Broccoli rubbed into skin was also found to prevent sunburn

Before heading out in the sun, most people apply a bit of sunscreen to their exposed skin.
However, a new study suggests that broccoli could be just as effective.

When rubbed directly into the skin, broccoli could also reduce the chance of a person developing skin cancer, the researchers believe.

Sally Dickinson, research assistant professor in the Pharmacology Department of the University of Arizona Cancer Centre, has teamed up with researchers from John Hopkins University in Baltimore for the pilot study.

Dr Dickinson said: ‘We’re searching for better methods to prevent skin cancer in formats that are affordable and manageable for public use.’

According to the team, the green vegetable contains a compound called sulforaphane which could help prevent skin cancer.

Sulforaphane is not only highly effective at inhibiting cancer-causing pathways – such as the AP-1 protein – it also triggers chemoprotective genes.

These genes protect healthy tissue from the toxic effects of the chemotherapy drugs that are used to combat cancerous growths.
Dr Dickinson said: ‘Sulforaphane may be an excellent candidate for use in the prevention of skin cancer caused by exposure to ultraviolet rays.

The green vegetable contains a compound called sulforaphane which could help prevent skin cancer by inhibiting cancer-causing pathways and triggering chemoprotective genes

‘It is the kind of compound that has so many incredible theoretical applications if the dosage is measured properly.

‘We already know that it is very effective in blocking sunburns and we have seen cases where it can induce protective enzymes in the skin.’

According to the American Cancer Society, skin cancer is currently the most common form of cancer in the U.S.

Excessive exposure to sunlight is thought to be one of the main causes of skin cancer, especially of the most aggressive form, malignant melanoma.

The researchers believe that their discovery could eventually lead to a reduction in the number of skin cancer cases.

Read more: http://www.dailymail.co.uk/health/article-2416605/Time-slap-BROCCOLI–Compound-vegetable-protect-sunburn-skin-cancer.html#ixzz2eZ4iYzlZ

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