Authors
Abhishek Thakur 1Subhash C. Mandal 2Sugato Banerjee 1,,
1Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, India
2Division of Pharmacognosy, Pharmacognosy and Phytotherapy Research Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India
Received 2 September 2015. Revised 24 January 2016. Accepted 28 January 2016. Available online 17 February 2016.
Abstract
A predominant number of diseases affecting women are related to female hormones. In most of the cases, these diseases are reported to be associated with menstrual problems. These diseases affect female reproductive organs such as the breast, uterus, and ovaries. Estrogen is the main hormone responsible for the menstrual cycle, so irregular menstruation is primarily due to a disturbance in estrogen levels. Estrogen imbalance leads to various pathological conditions in premenopausal women, such as endometriosis, breast cancer, colorectal cancer, prostate cancer, poly cysts, intrahepatic cholestasis of pregnancy, osteoporosis, cardiovascular diseases, obesity, etc. In this review, we discuss common drug targets and therapeutic strategies, including acupuncture and compounds of natural origin, for the treatment of diseases caused by estrogen deficiency.
http://ac.els-cdn.com/S2005290116000388/1-s2.0-S2005290116000388-main.pdf?_tid=57a40d74-401e-11e6-b838-00000aacb362&acdnat=1467441154_f8b6836711df9767e7ab0d3dee137954
Source: Science Direct
