Reishi, Ganoderma lucidum, Ling Zhi

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Any references here to treat or treatment are confined to the article or research as presented.

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Reishi, Ganoderma lucidum, Ling Zhi

Postby herbsandhelpers » Sat May 22, 2010 12:00 am

How Ganoderma Lucidum improves your health

In a Chinese medical encyclopedia "Bencao Gangmu", an ancient medical practitioner Lee Shizhen from Ming Dynasty classified Ganoderma as the "superior herb".

According to the record, "continuous consumption of Ganoderma makes your body light and young, lengthening life and making you like an immortal who never dies".

Modern researches

We may regard ancient medical text as unsound finding. However, it is interesting to discover that even modern researches proved most of the ancient findings on Ganoderma Lucidum herb.

Chinese scientists began investigating the chemical makeup and medicinal effects of Ganoderma Lucidum in 1950s. They supported their findings with clinical studies. Researcher from China, Japan, Korea and United States have also formed an international Ganoderma research association, bringing its research to global platform.

Ganoderma Lucidum Health Benefits

Scientists researched the special healing effects of Ganoderma herb on circulatory system, nervous system and immune system as well as its anti-cancer effects. Studies show it can significantly:

improve your blood circulation
calm your nerves
enhance your immune system
improve cancer healing chances

Your body operates on these major systems. If not properly regulated, you may fall ill. Ganoderma herb helps to regulate your various body systems, maintain stability and ensure a balance between internal and external body conditions.

Besides this, Ganoderma also has other important functions in your body...

Detoxify and energize your body

Ganoderma can also eliminate toxins accumulated in your body through intake of various western medication, antibiotic, pain killer and anti inflammatory medicines. It thus achieves a strong detoxification effect to maintain your body balance.

And in this fast paced modern world, people are subjected to extensive pressure resulting in tension, insomnia, giddiness, fatigue and loss of appetite.

The Organic Germanium in Ganoderma helps to enhance your blood stream ability to take in oxygen by more than 1.5 times. It also increases your metabolism rate and slow down your aging.

According to research by Japanese doctor, the concentration of Organic Germanium in Ganoderma is about 800 to 2000 ppm (parts per million), which is 4 to 6 times much higher than Ginseng.

Slow down your aging

In addition, Ganoderma Lucidum also contains Polysaccharides which help to strengthen your immune system. Hence the stabilizing effects of Ganoderma can strengthen your health, improve your vitality and improve your immune system.

With this, Ganoderma Lucidum herb obviously help to slow down your aging process.

And this is the essence of ancient medical classic that states, "continuous consumption of Ganoderma makes your body light and young, lengthening life and making you like an immortal who never dies".

1) Strengthen immune system

Why strengthening immune system is so important? Consider this...

Hepatitis virus causes liver hardening and eventually liver cancer
Helicobacter pylori virus causes stomach ulcer and eventually stomach cancer
Human papillomavirus (HPV) causes woman cervical cancer
Epstein-Barr virus (EBV) causes nasal cancer


You and I are mostly likely to get one of those viruses mentioned above in our life time. But we still don't get any of those diseases. Why?

Because your immune system had completely wiped out those invaders before they damage your body. Actually, it works every second to protect you from infection by germs and viruses, even when you're asleep.

Lowering of immunity causes all kind of diseases including cancer. So stengthening immune system is the first important healing requirement.

Ganoderma herb can effectively strengthen and regulate your immunity with its Organic Germanium, Polysaccharides and Triterpenes.

However, most health care supplements only focus on improving immune system. By focusing solely on this aspect, can we heal patient with stroke or high blood pressure?

Of course not! It's useless to strengthen their immune system. Their problems are caused by blood circulation blockage. That's why we need the next healing principle...

2) Remove circulatory blockage

This is what happen in your body when you have circulation blockage. Your blood cannot transport oxygen and nutrients to organ. The cells are crying in hunger and they die one by one. Toxics cannot be transfered out. And your body cells may die of toxic suffocation.

The accumulation of cholesterol, fats and blood clots slowly narrow down blood vessels and eventually block it completely. This is the condition of high blood pressure, stroke and heart vessels blockage.

In this case, you must remove the circulatory blockage for smoother circulation, stronger organ and better detoxification.

Ganoderma herbs are very potent in improving blood circulation and remove circulatory blockage with its Triterpenes and Adenosine Monophosphate (AMP).

Besides this, some diseases are still incurable with the above two healing principles. Therefore, we need a third one...

3) Enhance body energy

Ganoderma Lucidum herb also effectively improve your body energy and enhance your organ function, especially the lung and liver. Other than this, one more important healing principle is to...

4) Neutralize and Remove Toxic

You must get rid of body toxics before actually healing your illness. Without neutralizing and removing body toxics, most diseases are hard to cure.

Ganoderma Lucidum herb plays an important role in neutralizing and removing body toxics such as heavy metals. As natural healing herb, this fungus is particularly effective because of its rich content of minerals especially Organic Germanium and strong natural antioxidant, Superoxide Dismutase (SOD).

Ganoderma the heavenly herb

Not many herb has all these healing functions covered. Some can only improve immune system. Some is only good for blood circulation. But Ganoderma Lucidum herb effectively covers all these four healing principles.

No wonder ancient Chinese calls Ganoderma the heavenly herb.

Most patients benefit from Ganoderma Lucidum because it is the basic herb for many health problems. However for some sicknesses, this herb alone is not effective enough. Depending on each individual condition, other natural healing herbs are prescribed together for faster recovery.

One advantage of Ganoderma Lucidum is that you can consume it for long term without any side effects. As an adaptogenic herb, it seeks to maintain your body balance while improving body constitution.

Reishi Ganoderma benefits and clinical experiments

According to Dr. Shigeru Yuji clinical experiments, Reishi Ganoderma benefits our health because of its basic functions.

1) Lowers cholesterol and amount of free fat in the blood

2) Reduces blood sugar level and restores pancreas functions

3) Stabilizes red cell membrane

4) Due to Reishi Ganoderma's Adenosine, it can lower platelet's accumulation, dissolve thrombus (blood clot) and prevent blood vessel blockage

5) Improves function of adrenal glands to maintain hormone balance

6) Elevates natural healing ability of the body, allowing the body to established a strong immune system

7) Prevents tissue cell and organs degeneration

8) Prevents senility and maintains a youthful constitution

9) Lowers the side effects of anti-hypertensive drug

10) Prevents allergy caused by antigens because this herb inhibits the histamine-releasing mast cell

11) Prevents cancer, treats cancer and inhibits cancer cell metastasis

a) Normalizes cell to prevent tissue degeneration
b) Prevents sudden death of cancer patients caused by embolism (blockage)
c) Remove blood circulation blockage for cancer medication, further increases drugs effectiveness
d) Relieves pain caused by cancer


Is it true that Reishi Ganoderma is the savior of modern diseases and is a "Universal Medicine" for all diseases?
By Yukio Naoi of Kyoto University Foodstuff Scientific Institute

"Is Reishi Ganoderma herb really a universal medicine?"

Let's not talk about diseases prevalent in history but of modern diseases. In order to find the answer, we have investigated this herb's functions over and over again for thirteen years. Satisfactory results were obtained.

The first issue is whether Reishi Ganoderma benefits all kinds of diseases.

Our reply is "Yes", because it is able to maintain the health of modern person. For an unhealthy person, this herb can affect the weakest parts of her body. To a patient, it can root out the source of sickness and allow recovery.

Reishi Ganoderma can change an imbalanced body to a healthy one. There is no difference among human races, ancient or modern people. This herb has the same effects on everyone all over the world.

If the patient's constitution conforms to Ganoderma herb, this is like a patent drug achieving its highest effects. In fact, we have not found any person who obtained negative effects or inefficient results.

To evaluate the efficacy of Reishi Ganoderma, some outstanding results obtained recently are analyzed below...

Ganoderma benefit on Cancer

Taking Ganoderma Lucidum herb together with chemotherapy may have significant results for patients who had surgery for breast cancer, colon cancer or gastric cancer
Reported by Dr. Hiroshi Kawai of Kinki University

The experimental subjects were patients who were treated improperly after surgery, and patients who were suffering from chemotherapy side effects.

After a mastectomy and chemotherapy, one patient’s face became very dark. After consuming Ganoderma Lucidum for two months, her color improved.

One patient’s limbs became paralyzed and swollen after a mastectomy.

After taking Ganoderma Lucidum for one month, numbness significantly improved.

Some patients used Ganoderma Lucidum together with some herbal medicines for ten days after a colostomy. Night sweats disappeared and appetite improved.

Some patients who had gastric cancer operation found themselves with low appetites. After taking this herb, their appetites improved.

In view of above clinical results, we can see this herb functions as a valuable supporting treatment together with chemotherapy. This precious fungus also reduces side effects of chemotherapy.

Ganoderma Lucidum prevents cancer metastasis, relieves pain and improve the chance for longevity
Ganoderma Lucidum from the Polypore fungus family is regarded as an effective cancer treatment in Japan, China, USA, Canada, USSR and Scotland. Some medical specialists in different countries are using the latest scientific instruments for clinical tests.

Examples are Prof. Ta-Cheng from Medical College of National Taiwan University, Prof. Cheng Hui-hua and Prof. Tung Ui-chi from Taipei Medical College.

The experimental results proved that Ganoderma Lucidum is effective in cancer treatment. Information from research reports on how this herb treats cancer are as follow…

1) The anti-cancer components are Polysaccharides and Organic Germanium.

2) It can strengthen stamina, elevate immune system and restrain cancer metastasis.

3) After undergoing surgery, it is helpful to patients with cancer such as esophageal cancer, gastric cancer, breast cancer, intestinal cancer and uterine cancer.

4) It can eliminate cancerous ascites (abnormal accumulation of serous fluid in the abdominal cavity), increase appetite and relieve pain of late stage cancer.

5) It can be used together with other cancer treatments such as surgery, radiation, or combined with chemo therapy. It has no side effects and is effective.

Based on the above clinical reports, we may see that this precious herb has cancer preventing, suppressing and curing qualities.

Most of us may have dental carries, myopia or cancer tendencies when we are young. These diseases may also develop at any time in our life. We should try our best to prevent them from occurring.

To prevent tooth decay, we should eat more calcium and avoid sweets. To avoid myopia, we should eat more vitamin A and avoid eye fatigue. If we want to prevent cancer, we should eat more Ganoderma Lucidum herb and avoid an imbalanced diet.

Ganoderma benefit on Diabetes and kidney

With Ganoderma Lucidum, diabetes is no more a terrible disease Most people said that once you have diabetes, your life will be tangled with it. However, we improved a number of cases with Ganoderma Lucidum herb.

As we know, insufficient insulin secretion is the main cause of diabetes, and this result in some serious complications.

Currently, Western physicians use insulin injections as the only treatment.

Though insulin is able to lower blood sugar level, symptoms reoccur very soon.

Furthermore, like cortisone hormone injection, it has many side effects. Insulin is unable to recover pancreas function and it speeds up the aging of the organ.

The Medical Research Institute of Kinki University found in yearly experiments that Ganoderma Lucidum has the same effect as insulin.

Accordingly, after taking this herb, not only can insulin deficiency be supplemented, it can also make the pancreas regain its original function. In addition, it does not have any side effects like injections do.

Ganoderma Lucidum may affect significant help for kidney disease

Kidney disease is one of the most difficult diseases to cure. They include acute or chronic nephritis, diabetic renal syndrome, nephrosis and rheumatic fever. These may due in part to high cholesterol count and high blood sugar level.

The kidneys are overloaded and blood can not reach renal capillaries. Nephrosis results, with edema, urine retention, fatigue and possibly serious uremia.

Prof. Fumio Tsurudani of Nagoya University Medical Institute, Japan did an experiment with patients suffering from renal disease to check the effectiveness of Ganoderma Lucidum. It was found that it could not only lower proteinuria and cholesterolemia, but could maintain renal proper function.

Ganoderma benefit on Hypertension

Why Ganoderma Lucidum herb is effective for both systolic pressure and diastolic pressure?

Dr. Shigere Yuji or Kinki University gives 5 explanations why this herb is effective for cardiovascular diseases:

a) Treat hypertension
b) Elevate blood pressure of hypotensive patients
c) Prevent arteriosclerosis, lowers cholesterol level
d) Prevent blood vessel blockage and dissolve thrombus (blood clot)
e) Reduce side effects of anti-hypertensive drug

Headache and shoulder pain caused by hypertension and arteriosclerosis are completely cured. High blood pressure also improved
Reported by Mr. Isao Tani from Medical Research Institute of Kinki University

The experimental subjects were predominantly hypertension patients. After taking Ganoderma Lucidum herb, blood pressure showed significant improvement. One patient with a reading of 180/96 had a reading of 126/94 after three months.

Such remarkable improvement is rarely seen without using anti-hypertensive medication.

Some female arteriosclerosis patients’ blood pressure dropped to 128/67 from 158/77 within three months. Their cholesterol level also improved from 269 to 242.

Some patients had hypertension with headache and shoulder pain. Their blood pressure dropped from 151/78 to 118/72 in one month. Headaches were eliminated.

A number of patients improved their high blood pressure and pain problems.

Based on the above results, we may see Ganoderma Lucidum is useful to hypertension patients. Using anti-hypertensive to lower blood pressure can lower the systolic pressure, but not the diastolic pressure.

Ganoderma can lower both. This is its outstanding quality.

Ganoderma Lucidum is also effective in treating cerebral vascular obstruction, cardiac infarction, cerebral apoplexy and angina pectoris
Reported by Mr. Uebara Kioshi or Kinki University

Taking Ganoderma Lucidum can reduce the serious symptoms of the above diseases without traditional treatment.

Among these cases was a patient with a right cerebral arterial obstruction which occurred twice. He received best results after taking this herb with Urokinase together. Complete mobility finally returned.

A patient suffering from cerebral vascular obstruction who was partially paralyzed could move more freely after taking it. His free fat and B-lipo protein value returned to normal.

Taking Ganoderma Lucidum can also improve the condition of cardiac patients. This proves that taking this herb with other drugs may result in better results. By the way, since the above diseases are difficult to cure, it is better to take Ganoderma regularly to prevent their occurring in the first place.

Ganoderma benefit on Liver

Ganoderma Lucidum herb is effective in treatment of acute or chronic hepatitis and other liver disease
Reported by Dr. Mitsui Hashimoto of Hashimoto Hospital

At present time, hepatitis is still a disease which cannot be effectively treated with any specific method. If Ganoderma Lucidum is effective, it would be a meaningful medicine for this liver disease.

Six capsules per day were prescribed to some patients with hepatitis.

There months later, all the patients were recovering. Their GOT and GPT values decreased from 200 – 300 to 100.

In addition, one patient who used Ganoderma Lucidum together with some Chinese herbal medicines saw a decreased GOT and GPT.

There was one case of hepatitis combines with hypertension. After taking this herb, satisfactory results were obtained.

The above conditions cannot be conclusive, but positive results on hepatitis can be expected. When liver function is declining, the patient may get tired. Taking Ganoderma helps to ease fatigue.

Ganoderma benefit on Woman's health

Ganoderma Lucidum is effective in treating gynecological problems such as menstrual cramps, vertigo and menopause disturbances
Reported by Dr. Yoshinori Imanishi of the Imanish Gynecology and Obstetrics Hospital

The writer, who is an OB-GYN specialist, prescribed Ganoderma Lucidum to women patients who had menstrual cramps, dizziness, irregular menstruation, menopause disturbances and difficulty in becoming pregnant.

There were three cases which had positive results...

A 46 year old woman took Ganoderma Lucidum for one month when her dizziness and shoulder pain was relieved.

A pregnant woman had tightness in her chest and no appetite. After treatment with this herb, her condition improved.

One woman with a physiological disorder was married for many years without conceiving. After taking Ganoderma Lucidum for three months, she became pregnant.

There are two cases where positive results were obtained from combining Ganoderma Lucidum and herbal medicines. In the first case, serious dizziness and shoulder pain was relieved in three months. In the second case, abdominal pain was reduced.

This herb can relieve postpartum symptoms, acting as a hemocatharsis, diuretic and detoxicant.

Ganoderma Lucidum is a required supplement for pregnant woman
When a daughter becomes pregnant, her parents may wonder if it is safe to give her Ganoderma Lucidum. The expectant mother may become moody, especially for the first pregnancy.

During pregnancy, women are quite sensitive to outer stimulation, both mentally and physically. Though it is a natural phenomenon, most women have difficulty adapting.

During this period, taking Ganoderma Lucidum may act as a hemocatharsis, diuretic, and detoxicant and will allow the fetus to develop normally. This herb may also help woman who is difficult to get pregnant or who had habitual abortion before.

Prof. Kanata of Tohoku University believes that taking this herb can strengthen sexual ability of both the male and female, intensifying the activity of spermatozoa and regulating ovulation of the female.

Information of different sources reveals that Ganoderma Lucidum may be thought of as "friend of the female". It should be considered a required supplement for women.

Ganoderma benefit on Pain

Pain from gastritis, gastric ulcer and duodenal ulcer can be relieved immediately
Reported by Dr. Taro Tamura of Kinki University

We used Ganoderma Lucidum in gastritis, gastric ulcer and duodenal ulcer treatment.

The most interesting case was a man who developed gastric ulcer when he was young and which had recently returned.

Other medicines were ineffective. But one week after beginning treatment with Ganoderma herb, his pain was significantly reduced.

When dosage was reduced, he felt pain once a day or almost no pain at all.

He usually used an analgesic but it seemed useless. This treatment is also effective for gastritis and duodenal ulcer patients who suffer from chest pain, loss of appetite and gastric ulcer patient who are fatigue and weak.

It can also help gastric cancer post-operation pain. Some patients’ color improved and they put on weight gradually after taking Ganoderma Lucidum.

Ganoderma Lucidum is effective in treating varicose veins on the waist and shoulders, and rheumatism of the hands and knees. It can also treat sciatica
Reported by Dr. Taro Kiyobara of Hospital of Plastic and Reconstructive Surgery

Ganoderma Lucidum can be used to treat low back pain, and pain of the hands, shoulders, and knees.

There is one case of varicose veins which improved a little. This herb is considerably effective in the treatment of pain caused by blood, blood vessels or hematoma (blood swelling) on the torso.

As to shoulder, neck and knee pain, in one patient, the pain originated from a deformed knee but the pain was relieved.

Treating pain which results from some structural factor, such as low back pain caused by herniated intervertebral disk, is ineffective.

Ganoderma Lucidum herb protects patients who overeat, eat only one kind of food or poisoned by food
It has surprising results in treating dysentery, constipation, gastric hyperacidity and peptic ulcer. Its effects are equal to that of medicines now in common use. Dr. Shigeru Yuji also reported its high efficacy in treating gastritis and ulcers.

The main function of the stomach and the intestines is to absorb the required nutrients in food, then excrete the wastes before fermentation. People usually eat too much, have an imbalanced diet, or consume toxic foods. This damages their digestive organs.

Ganoderma Lucidum can not only protect the organs but can improve the functioning of the digestive tract.

Ganoderma benefit on Other diseases

Many kinds of hereditary diseases have high occurrence rate. If you are healthy at this moment, you want to maintain this condition all your life. Ganoderma Lucidum can help you to reach this goal.

Ganoderma Lucidum’s outstanding feature is that “It can adequately reflect slight symptoms of diseases, keeping the human body in harmonious condition”.

This expression is the conclusion obtained from experiments on thousands of people.

Ganoderma Lucidum is a kind of medicinal food with over two thousand years of human experience. After long term experiments, its pharmacological nature has been further clarified.

This herb is widely used to maintain the health of human beings. Now, its position in medical field has been firmly established.

Ganoderma Lucidum is also effective in treatment of difficult and mysterious diseases
For example,

a) No cause can be found

b) Even if the cause can be found, it is untreatable with drugs. For example, blood pressure disorders are caused by many factors. But it is too complicated to understand the source and eliminate it. Even though anti-hypertensive drugs can relieve the symptoms, the source can not be eliminated.

For diseases which cannot be treated adequately with medicine and cannot be diagnosed, Ganoderma Lucidum can be considered a precious solution.

Ganoderma Lucidum may treat these diseases successfully, eliminating the root cause of various puzzling diseases.

Ganoderma clinical experiment on Promoting longevity

Best Antioxidant Herb

The above tests show that Ganoderma is one of the best antioxidant herb beneficial in boosting the overall antioxidant power of the blood. In addition, this herb reinforces human body’s ability to get rid of free radicals and toxins.

Furthermore, Ganoderma is also exceptional in elevating the survival rate of the hippocampus gyrus in the brain to help improve our memory power and learning faculty.

Scientific findings of extensive research works on Ganoderma carried out in the last 40 years have indicated that Ganoderma is capable of imparting human body with holistic health enhancing benefits.

As our forefathers had already put it concisely, Ganoderma is indeed helpful in "restoring normal physiological functions to consolidate the physical constitution".

Hence, long term consumption of Ganoderma can contribute to boosting the antioxidant power of our multi enzymatic system. It also helps to rid of the free radicals to eliminate "oxidative stress" and enhance your vitality.

Following this, the level of vitality achieved can effectively minimize the harm of free radicals and get rid of them in the shortest possible time. This is indeed the key to retarding the ageing process or "promoting longevity".

Please note that healing results differ from person to person depending on heredity factor, sickness duration, disease severity, diet, emotional factor, environment and many other factors.

General....

Reishi mushroom is used for boosting the immune system; viral infections such as the flu (influenza), swine flu, and avian flu; lung conditions including asthma and bronchitis; heart disease and contributing conditions such as high blood pressure and high cholesterol; kidney disease; cancer; and liver disease. It is also used for HIV/AIDS, altitude sickness, chronic fatigue syndrome (CFS), trouble sleeping (insomnia), stomach ulcers, poisoning, and herpes pain. Other uses include reducing stress and preventing fatigue.

In combination with other herbs, reishi mushroom is used to treat prostate cancer.

How does it work?

Reishi mushroom contains chemicals that seem to have a variety of potentially beneficial effects, including activity against tumors (cancer) and beneficial effects on the immune system.

Herpes-related pain. Some people report that hot water extracts of reishi mushroom decreases pain when conventional treatment doesn’t work.
Boosting the immune system.

High blood pressure.
High cholesterol.
Viral infections.
Tumors.
Prostate cancer.
Heart disease.
Asthma and bronchitis.
Stress.
Kidney disorders.
Liver disease.
HIV disease.
Altitude sickness.
Fatigue.
Chronic fatigue syndrome (CFS).
Trouble sleeping (insomnia).
Stomach ulcers.
Poisoning.
Shingles.
Other conditions.

More evidence is needed to rate the effectiveness of reishi mushroom for these uses. (See references)

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of reishi mushroom during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Low blood pressure: Reishi mushroom seems to be able to lower blood pressure. There is a concern that it might make low blood pressure worse and could interfere with treatment. If your blood pressure is too low, it’s best to avoid reishi mushroom.

A clotting disorder called thrombocytopenia: High doses of reishi mushroom might increase the risk of bleeding in people with thrombocytopenia. If you have this condition, don’t use reishi mushroom.

Interactions

Medications for high blood pressure (Antihypertensive drugs) interacts with REISHI MUSHROOM

Reishi mushroom might decrease blood pressure. Taking reishi mushroom along with medications for high blood pressure might cause your blood pressure to go too low.

Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), and many others.

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with REISHI MUSHROOM

High doses of reishi mushroom might slow blood clotting. Taking reishi mushroom along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

References:

el-Mekkawy S, Meselhy MR, Nakamura N, et al. Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochem 1998;49:1651-7.

Gao Y, Zhou S, Jiang W, et al. Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients. Immunol Invest 2003;32:201-15.

Gau JP, Lin CK, Lee SS, et al. The lack of antiplatelet effect of crude extracts from ganoderma lucidum on HIV-positive hemophiliacs. Am J Chin Med 1990;18:175-9.

Hijikata Y, Yamada S. Effect of Ganoderma lucidum on postherpetic neuralgia. Am J Chin Med 1998;26:375-81.

Hikino H, Ishiyama M, Suzuki Y, et al. Mechanisms of hypoglycemic activity of ganoderan B: a glycan of Ganoderma lucidum fruit bodies. Planta Med 1989;55:423-8.

Kim DH, Shim SB, Kim NJ, et al. Beta-glucuronidase-inhibitory activity and hepatoprotective effect of Ganoderma lucidum. Biol Pharm Bull 1999;22:162-4.

Kim HS, Kacew S, Lee BM. In vitro chemopreventive effects of plant polysaccharides (Aloe barbadensis miller, Lentinus edodes, Ganoderma lucidum and Coriolus versicolor). Carcinogenesis 1999;20:1637-40.

Kim RS, Kim HW, Kim BK. Suppressive effects of Ganoderma lucidum on proliferation of peripheral blood mononuclear cells. Mol Cells 1997;7:52-7.

Komoda Y, Shimizu M, Sonoda Y, et al. Ganoderic acid and its derivatives as cholesterol synthesis inhibitors. Chem Pharm Bull (Tokyo) 1989;37:531-3.

Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6.

Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64.

Min BS, Nakamura N, Miyashiro H, et al. Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease. Chem Pharm Bull (Tokyo) 1998;46:1607-12.

Reishi. Mothernature encyclopedia. www.mothernature.com/ency/herb/reishi.asp. (Accessed 7 November 1999).

Singh AB, Gupta SK, Pereira BM, et al. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.

Sun J, He H, Xie BJ. Novel antioxidant peptides from fermented mushroom Ganoderma lucidum. J Agric Food Chem 2004;52:6646-52.

Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3.

van der Hem LG, van der Vliet JA, Bocken CF, et al. Ling Zhi-8: studies of a new immunomodulating agent. Transplantation 1995;60:438-43.

Wang SY, Hsu ML, Hsu HC, et al. The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes. Int J Cancer 1997;70:699-705.

Wasser SP, Weis AL. Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective. Crit Rev Immunol 1999;19:65-96.

Yoon SY, Eo SK, Kim YS, et al. Antimicrobial activity of Ganoderma lucidum extract alone and in combination with some antibiotics. Arch Pharm Res 1994;17:438-42.

Yuen JW, Gohel MD. Anticancer effects of Ganoderma lucidum: a review of scientific evidence. Nutr Cancer 2005;53:11-7.
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