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Ge Gen (100g)
[H8250]

Common Name - Kudzu, Pueraria Root
Latin/Pharm. Name - Puerariae
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DESCRIPTION: KPC 5:1 Concentrated Extract Granules. (RETAIL PRICE)

Non-Irradiated Herbs: All our current sources and suppliers confirm or certify that they never supply irradiated herbs or herbal materials.

Your Safety: We confirm that we are fully CITES compliant, all KPC herbals have independent EU COA from laboratory in Brussels and total traceability.

AVAILABILITY: Available. Ordered per shipment, check on current stocks.

DESCRIPTION:

Pharmaceutical name:

Radix Puerariae

Botanical name:

Pueraria lobata (Willd.) Ohwi, Pueraria thunbergiana (S. etZ.) Benth., Pueraria hirsuta (Thunb.) Schneid., Pueraria pseudohirsuta Tang et wang, Pueraria thomsonii Benth.(Family: Fabaceae)

Common Name:

Kudzu root, Pueraria

Distribution:

Hunan, Henan, Guangdong, Zhejiang, Southeast Asia, North America.

Properties (characteristics):

Acrid, Sweet, Neutral

Channels (meridians) entered:

Spleen, Stomach

Medical Functions:

1. Effect on smooth muscle: Ge gen root contains ingredients that can contract and relax smooth muscle. The ingredients that can cause contraction can be choline, acetylcholine, and kassein other substances. In ge gen ether extract, components of smooth muscle relaxation, daidzin and daidzein were separated, which could significantly inhibit mouse ileum contraction induced by acetylcholine. Its effectiveness is about 1/3 of that of papaverine. Since ge gen mainly containing flavonoids, particularly daidzein which possesses anti-acetylcholine effect, clinically it is mainly used in relieving spasm.
2. Anti-diarrhea
3. Effect on coronary blood vessels: the active ingredient puerarin relaxes the coronary and cerebal blood vessels
4. Anti-arrhythmia
5. Enhances the function of the heart
lowers Blood pressure and lowers the resistance of peripheral blood vessels
6. Beta energetic blocking effect (see 6.)
7. Inhibits platelet coagulation
8. Lower blood sugar
9. Inhibits growth of cancer cells and induces differentiation of cancer cells. (Normally cancer cells do not differentiate, so it never loses its potential for growth. )
10. Anti-oxidation
11. Improves memory: Effects on memory: According to Liu Ganzhong et el, using mice and rats jumping method and operant conditioning method to observe the ge gen alcohol extract and flavonoids in learning and memory function in animals. Memory results in mice, both of which can fight scopolamine (hydrobromide Scopolamine) and 40% ethanol that induced memory disorders. Alcohol extract of ge gen still capable of fighting scopolamine-induced rat operant conditioning reflex inhibition. The study found that scopolamine reduces mouse cortical and hippocampal acetylcholine content and decreased hippocampal acetylcholine transferase activity. This may be why ge gen can improve learning and memory mechanisms.[1]
12. Biphasic body temperature regulation[1]
13. Improves eyesight[1]
14. Lactagogue
15. Possesses 2 directional adjustment of nitric oxide. It can protect the heart during heart attack.
16. It can be used for treatment of schizophrenia.
17. Preventative therapeutics for brain disorders due to their abilities to promote the neuronal cytoarchitecture and the synaptic functionality [4]

Actions & Indications:

Diaphoretic (producing or increasing perspiration), antispasmodic, muscle relaxant, antipyretic, help to ripen measles, stopping diarrhea.

Being used in fever and headache in cold or flu, spastic muscles, thirst, diabetes, diarrhea, acute ileus (intestine blockage), measles ripening difficulty, in alcohol hangover, alcohol withdrawal, angina, hypertension, smoking, alcohol, early stage of acute deafness, menopause syndrome, cerebral palsy [5].

Young shoots are used as a lactagogue.

Ge gen starch is being used in treating diarrhea. Do not add sugar to the starch. See the picture of a commercial package of starch here.

Chemical ingredients:

Flavonoids: 7-xyloside puerarin, 3'-hydroxypuerarin, formononetin, genistein, methylpuerarin, daidzein, daidzin, puerarin, puerarin-7-xyloside, 4’-6’-O-diacetylpuerarin, 7,4′-diglucoside, xylopueratin, miroestrol

Glicoside: 4-O-D-glucoside, 8-C-apiosyl-glucosides, pueroside A, B, pueranol

Triterpenoids: Sophoradiol, soyasapogenols A, B, cantoniensistriol

Alkaloid: Kassein

Saccharides: Starch (10-15%), D-mannitol, D-(±)pinitol

Saponins: β-sitosterol, kudzusapogenol A, B, C, 6,7-dimethoxycoumarins, 5-methylhydrantoin, Arachidic acid

Dosage:

3 - 12g Dried herb. If using fresh herb the amount can be few times more..

Samples of formulae:

For influenza, pneumonia, bronchitis, headache, chronic shoulder pain, skin inflammation, rheumatism, and smell disappears after flu or cold.
Name of Formula: Ge Gen Tang

For: damp-heat with diarrhea:
Name of Formula: Ge Gen Qin Lian Tang(5)。

For small children spitting milk or diarrhea due to weak digestion. Also can be used in women for loose breasts with condition of pixu (spleen deficient) condition.
Name of Formula: Qi Wei Bai Zhu San

Alcohol Intoxication:
Formula 1: Smash fresh Ge Gen root to get juice to make drink (Qian Jin Fang)
Formula 2: Use Ge Gen starch to make porridge

Modern Usage:

Ge gen was first described in the Chinese materia medica, Shen Nong Ben Cao (200 B.C.). Both the roots and flowers of ge gen have been used to treat alcohol abuse, drunkenness, and hangover ( "jiu du" or alcohol poisoning) safely and effectively in China for more than a millennium. [1] Now it has been tested in addiction to smoking and is considered to have the same effect, reducing the addiction in a month time. Puerarin promotes osteoblast to differentiate by influencing the activity of ALP and promotes bone formation by the meditation of estrogen receptor. [1] Being used in heart and brain diseases due to lack of blood circulation.
Effects on coronary: Ge gen decoction, alcohol extract, total flavonoids, and puerarin have significant expansion of coronary blood vessels effect.
Effect on smooth muscle: Ge gen contains ingredients that can contract and also relax of smooth muscle. The ingredients that cause constraction can be choline, acetylcholine and kassein R and other substances. The ether extract of ge gen can cause smooth muscle relaxation. The ingredients have been proven to be glycitein and daidzein. They clearly can inhibit the acetylcholine-induced ileum contraction of mice, and the effectiveness is about one third of that of papaverine. Because ge gen mainly containing flavonoids, particularly daidzein with anti-acetylcholine effect, the clinical use of ge gen is mainly for antispasmodic.

Cautions and toxicity:

Allergy reaction of injectiones of puerarin: There are cases of hemolytic reaction and resulted in death. Not to use in cases of instant sweating during summer. Using too much can damage the digestive function.

In prescription:

References:

[1]( 据崔蘇镇等“葛根的藥 理作用 研 究概况”----時珍國藥 研究 1998 9(3):279-280)
[2] 遼寧中醫雜誌>33卷6期 劉振杰;曹 雅靜;曹幸餘
[3] Zhong Hua Ben Cao 中華本草
[4] J Ethnopharmacol. 2015 Jul 18. pii: S0378-8741(15)30030-1. doi: 10.1016/j.jep.2015.07.013. [Epub ahead of print] http://www.ceps.com.tw/ec/ecjnlarticleView.aspx?atliid=376225&issueiid=28832&jnliid=2479
[5] J Chin Med 24(1): 121-127, 2013

Source: Courtesy of Complementary and Alternative Healing University

AVAILABILITY: Available. Ordered per shipment, check on current stocks.

To access knowledge base entries, click a keyword:
KEYWORDS: Ge Gen, Puerariae, ,

Keywords allow the website to work only. They in no way are meant to indicate advice or treatment of any kind. Please read our disclaimer. Always visit your GP or practitioner regarding any health issues.


Available. Ordered per shipment, check on current stocks.
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